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authorWen Heping <wen@FreeBSD.org>2012-11-15 07:04:29 +0000
committerWen Heping <wen@FreeBSD.org>2012-11-15 07:04:29 +0000
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-The LAGAN Toolkit consists of four components:
-
- CHAOS, a pairwise local aligner optimized for non-coding, and other
- poorly conserved regions of the genome.
-
- LAGAN, a highly parametrizable pairwise global alignment using local
- alignments generated by CHAOS as anchors.
-
- Multi-LAGAN, a progressive pairwise algorithm to produce multiple
- sequence alignments.
-
- Shuffle-LAGAN, a novel glocal algorithm that is able to find
- rearrangements in a global alignment.
-
-Fast and sensitive multiple alignment of long genomic sequences. BMC
-Bioinformatics 2003 4:66.
-
-LAGAN and Multi-LAGAN: efficient tools for large-scale multiple
-alignment of genomic DNA. Genome Res 2003 13(4): 721-31.
-
-Glocal alignment: finding rearrangements during alignment. Proceedings
-of the ISMB 2003, Bioinformatics 19: 54i-62i.
-
-WWW: http://lagan.stanford.edu/lagan_web/
+The Lagan Tookit is a set of alignment programs for comparative
+genomics. The three main components are a pairwise aligner (LAGAN), a
+multiple aligner (M-LAGAN), and a glocal aligner (Shuffle-LAGAN). All
+three are based on the CHAOS local alignment tool and combine speed
+(regions up to several megabases can be aligned in minutes) with high
+accuracy. The results of the alignment can be visualized using the VISTA
+visualization tool.
+
+WWW: http://lagan.stanford.edu/