Bitshuffle is an algorithm that rearranges typed, binary data for improving compression, as well as a python/C package that implements this algorithm within the Numpy framework. The library can be used along side HDF5 to compress and decompress datasets and is integrated through the dynamically loaded filters framework. Bitshuffle is HDF5 filter number 32008. Algorithmically, Bitshuffle is closely related to HDF5's Shuffle filter except it operates at the bit level instead of the byte level. Arranging a typed data array in to a matrix with the elements as the rows and the bits within the elements as the columns, Bitshuffle "transposes" the matrix, such that all the least-significant-bits are in a row, etc. This does not in itself compress data, only rearranges it for more efficient compression. To perform the actual compression you will need a compression library. Bitshuffle has been designed to be well matched to Marc Lehmann's LZF as well as LZ4 and ZSTD. Note that because Bitshuffle modifies the data at the bit level, sophisticated entropy reducing compression libraries such as GZIP and BZIP are unlikely to achieve significantly better compression than simpler and faster duplicate-string-elimination algorithms such as LZF, LZ4 and ZSTD. Bitshuffle thus includes routines (and HDF5 filter options) to apply LZ4 and ZSTD compression to each block after shuffling.