PEAK-Rules is a highly-extensible framework for creating and using generic functions, from the very simple to the very complex. Out of the box, it supports multiple-dispatch on positional arguments using tuples of types, full predicate dispatch using strings containing Python expressions, and CLOS-like method combining. (But the framework allows you to mix and match dispatch engines and custom method combinations, if you need or want to.) WWW: https://pypi.python.org/pypi/PEAK-Rules