PyDal is a database abstraction layer for Python.  It provides a DBAPI 2.0 
wrapper for DBAPI 2.0 drivers.  Sounds strange, but even drivers that fully 
conform to the DBAPI can differ enough to make building database independent 
applications difficult.  Two major abstractions handled by PyDal are 
paramstyles and datetime objects.  PyDal makes it possible to use the same 
paramstyle and datetime types with any module that conforms to DBAPI 2.0. 
In addition, paramstyles and datetime types are configurable.

WWW: http://pydal.sourceforge.net/