You now need to add an alias to apache's httpd.conf pointing to %%SQUIRRELDIR%% in order to access SquirrelOutlook from your web browser, or create a VirtualHost with DocumentRoot set to that directory. For SquirrelOutlook to work properly you will need to make sure the following option is set in your php.ini file: file_uploads = On If you have problems with SquirrelOutlook saying "you must login" after you just have, the following php.ini option may help: session.auto_start = 1 In order to do your administrative configuration you need to cd %%SQUIRRELDIR%% && ./configure SquirrelOutlook will not work until this has been done.